SIGA Technologies Inc. (SIGA): CHRISTINA HUTSON, CDC [00:20:10] Becau...

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axelvento

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Tuesday, 11/15/2022 11:22:20 PM

Tuesday, November 15, 2022 11:22:20 PM

CHRISTINA HUTSON, CDC [00:20:10]
Because of these findings, from the start of the outbreak, we have been monitoring the F13L gene within sequenced isolates. At this time, CDC has analyzed sequence data for more than 4,000 specimens from across the United States, of which 11 were found to have genetic changes in the F13L gene during those sequence surveillance efforts.
When tested within the lab, using a cell culture based sensitivity assay, those 11 isolates were sensitive to tecovirimat, showing no evidence of resistance.
We’re currently working on a health advisory related, in part, to development of tecovirimat resistance virus during prolonged tecovirimat treatment. We wanted to let everyone know that this would be coming out soon, and there’ll be more information for providers about the potential for tecovirimat resistance.

-And we hope to have that HAN out by the middle of next week-

https://www.getrevue.co/profile/alexander_tin/issues/notes-for-11-14-2022-1459787