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Wednesday, 10/19/2022 3:57:09 PM

Wednesday, October 19, 2022 3:57:09 PM

Post# of 14947
Pfizer's PAXLOVID has done a lot of good and sales exceed $22 Billion this year. But if the costs are not covered by government it is costly ($500+ for a course of treatment) and there are health warnings.
Sorrento's Mpro should be far cheaper (it is far less costly to produce) and it appears not to require the drug/drug interaction warnings that accompany Paxlovid. Here are some of the warnings...

"Do not take PAXLOVID if:
You are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID.
You are taking any of the following medicines:
alfuzosin
amiodarone
apalutamide
carbamazepine
clozapine
colchicine
dihydroergotamine
dronedarone
eletriptan
eplerenone
ergotamine
finerenone
flecainide
flibanserin
ivabradine
lomitapide
lovastatin
lumacaftor/ivacaftor
lurasidone
methylergonovine
midazolam (oral)
naloxegol
pethidine
phenobarbital
phenytoin
pimozide
primidone
propafenone
quinidine
ranolazine
rifampin
St. John’s Wort (hypericum perforatum)
sildenafil (Revatio®) for pulmonary arterial hypertension
silodosin
simvastatin
tolvaptan
triazolam
ubrogepant
voclosporin

Taking PAXLOVID with these medicines may cause serious or life-threatening side effects or affect how PAXLOVID works.
These are not the only medicines that may cause serious side effects if taken with PAXLOVID. PAXLOVID may increase or decrease the levels of multiple other medicines. It is very important to tell your healthcare provider about all medicines you are taking because additional laboratory tests or changes in the dose of your other medicines may be necessary while you are taking PAXLOVID. Your healthcare provider may also tell you about specific symptoms to watch out for that may indicate that you need to stop or decrease the dose of some of your other medicines.

Possible side effects of PAXLOVID are:
Allergic Reactions. Allergic reactions can happen in people taking PAXLOVID, even after only 1 dose. Stop taking PAXLOVID and call your healthcare provider right away if you get any of the following symptoms of an allergic reaction:
hives
trouble swallowing or breathing
swelling of the mouth, lips, or face
throat tightness
hoarseness
skin rash
Liver Problems. Tell your healthcare provider right away if you have any of these signs and symptoms of liver problems: loss of appetite, yellowing of your skin and the whites of eyes (jaundice), dark-colored urine, pale-colored stools and itchy skin, or stomach area (abdominal) pain.
Resistance to HIV Medicines. If you have untreated HIV infection, PAXLOVID may lead to some HIV medicines not working as well in the future.
Other possible side effects include:
altered sense of taste
diarrhea
high blood pressure
muscle aches
abdominal pain
nausea
feeling generally unwell
These are not all the possible side effects of PAXLOVID. Not many people have taken PAXLOVID. Serious and unexpected side effects may happen. PAXLOVID is still being studied, so it is possible that all of the risks are not known at this time.
There is no experience treating pregnant women or breastfeeding mothers with PAXLOVID. For a mother and unborn baby, the benefit of taking PAXLOVID may be greater than the risk from the treatment. It is recommended that you use effective barrier contraception or do not have sexual activity while taking PAXLOVID. If you are pregnant or breastfeeding, discuss your options and specific situation with your healthcare provider.'

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