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Re: runncoach post# 20312

Friday, 10/07/2022 1:28:32 PM

Friday, October 07, 2022 1:28:32 PM

Post# of 21523
From the TauRx press release:

"The overall baseline MMSE score was 21 for the study population spanning MCI through to moderate disease. There was minimal decline over the first 12 months in participants receiving the 16 mg/day dose on both coprimary cognitive and functional endpoints (1.3 ADAS-cog11 units and -1.0 ADCS-ADL23 units). The expected decline over 12 months in an untreated population would be approximately 5 units on both scales."

Am I reading this correctly, that they expect a 5 unit (point) decline in MMSE in the course of a year, starting from a level of 21?

Seems a tad high expected decline?

Also, I wonder what this would translate to in SIB decline?
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