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Re: olivernoyes post# 2273

Thursday, 10/06/2022 2:15:24 PM

Thursday, October 06, 2022 2:15:24 PM

Post# of 2339
Lots of different industry news below...

This new paper below shows that CBD does not convert into THC in the stomach as some have suggested. This may be an important and positive finding for the industry...

"Will tetrahydrocannabinol be formed from cannabidiol in gastric fluid? An in vivo experiment":
2022 Oct 3

Abstract
Cannabidiol (CBD) products have ascribed an uprising trend for their health-promoting effects worldwide. In contrast to ?9-tetrahydrocannabinol (THC), CBD exhibits no state of euphoria. Since conversion of CBD into THC in an acidic environment has been reported, it has not been proved whether this degradation will also occur in human gastric fluid. A total of 9 subjects ingested 400 mg CBD as a water-soluble liquid together with lecithin as an emulsifier and ethanol as a solubilizer. Blood samples were taken up to 4 h, and urine samples were submitted up to 48 h. THC, 11-hydroxy-?9-THC (THC-OH), 11-nor-9-carboxy-?9-THC (THC-COOH), CBD, 7-hydroxy cannabidiol (7-OH-CBD), and 7-carboxy cannabidiol (7-CBD-COOH) were determined in blood and THC-COOH and 7-CBD-COOH in urine by LC-MS/MS. Neither THC, THC-OH, nor THC-COOH were detectable in any serum specimen. Only two urine samples revealed THC-COOH values slightly above the threshold of 10 ng/ml, which could also be caused by trace amounts of THC being present in the CBD liquid. It can be concluded that negative consequences for participants of a drug testing program due to a conversion of CBD into THC in human gastric fluid appear unlikely, especially considering a single intake of dosages of less than 400 mg. Nevertheless, there is a reasonable risk for consumers of CBD products being tested positive for THC or THC metabolites. However, this is probably not caused by CBD cyclization into THC in human gastric fluid but is most likely due to THC being present as an impurity of CBD products.


https://pubmed.ncbi.nlm.nih.gov/36190564/

"U.S. Cannabis: SAFE Plus Passage Is Possible In The Lame Duck, According To Cantor":
Oct 4, 2022
https://thedalesreport.com/cannabis/u-s-cannabis-safe-plus-passage-is-possible-in-the-lame-duck-according-to-cantor/

Reminder...FDA response requested by congress by 10/17...

"Griffith, Guthrie Call For Answers From FDA":
SEPTEMBER 19, 2022

Congressman Morgan Griffith (R-VA) and Congressman Brett Guthrie (R-KY) today sent two letters to Food and Drug Administration (FDA) Commissioner Dr. Robert Califf posing questions about numerous FDA regulatory lapses and calling for answers.


One of the letters focuses on FDA’s Center for Food Safety and Applied Nutrition (CFSAN) and its failures to ensure a safe and adequate infant formula supply. That letter can be viewed here.
https://morgangriffith.house.gov/uploadedfiles/cfsan_letter_9.19.22.pdf

The other letter focuses on lapses by CFSAN and the Center for Tobacco Products regarding cannabidiol (CBD), CBD-derived products, and tobacco products. That letter can be viewed here.
https://morgangriffith.house.gov/uploadedfiles/ctp_cfsan_letter_9.19.22.pdf

Responses to both letters are requested by October 17, 2022.


https://nrvnews.com/griffith-guthrie-call-for-answers-from-fda/

"Legalized marijuana market estimated to be worth $64 billion in US: Report":
October 6, 2022

A recent study by Coresight Research suggests that the marijuana market has nearly tripled over the previous three years as legalization spreads across the United States.

According to the report’s findings, 22% of the 1,017 survey participants from the 41 states (plus the District of Columbia) where marijuana is currently legal in some form reported having bought it for recreational or therapeutic purposes over the previous 12 months.

It also suggests that participants’ average monthly spending was $85; 1 in 4 spent less than $30, while 9% spent $200 or more.

As a result, Coresight projected that the market is now valued at around $64.3 billion yearly, up from $21.5 billion in 2019.

Two-thirds of marijuana users claimed that their use had grown since marijuana was legalized, 57% of those consumers claimed to have smoked it, 46% to have eaten it, and 42% to have vaped it.


https://minutemirror.com.pk/legalized-marijuana-market-estimated-to-be-worth-64-billion-in-us-report-65783/

Here is a podcast people can subscribe to from Jonathan Miller of U.S. Hemp Roundtable...
"Hemp Legally Speaking!":
https://www.hemplegallyspeakingpodcast.com/
https://www.hemplegallyspeakingpodcast.com/episodes

"Key congressional races the marijuana industry should watch":
October 5, 2022

https://mjbizdaily.com/key-congressional-races-the-marijuana-industry-should-watch/

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