Beyond Air Inc (XAIR)

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How is nitric oxide stored in the human body?
Nitric oxide does not usually exist in its free form in the body due to its unstable nature but reacts with other molecules to form more stable products.

In the blood, nitric oxide has a very short half-life and rapidly oxidises to nitrite. It is then further oxidised with oxyhaemoglobin to produce nitrate. Nitric oxide also reacts directly with oxyhaemoglobin to produce methhaemoglobin and nitrate.
Reactions with cysteine residues in proteins lead to formation of nitrosylated products. Because of its high affinity to sulfhydryl groups (thiols), S-nitrosothiols (RSNOs) are the most common nitrosylated product in plasma.
Nitrate is the main storage form of nitric oxide. It is very stable when compared with other storage forms such as nitrites and RSNOs, which are important carriers and donor molecules of nitric