Humanigen Inc (HGENQ)

[cowtown jay]

The covid "superdodger" post Preciouslife1 linked to start this thread is about research at UCSF designed to answer the question, "So why haven't these (exposed) people caught COVID?"

The lead researcher looking into this question is immunogeneticist Jill Hollenbach. She "... and her colleagues at UCSF have been studying people who test positive COVID but show no symptoms. "Not even a sniffle or a scratchy throat," she says. "So they are entirely asymptomatic."

After analyzing DNA from more than 1,400 people, they identified a mutation that helps a person clear out SARS-CoV-2 so fast that their body doesn't have a chance to develop symptoms.

The mutation occurs in a gene called HLA, which is critical during the earliest stages of infection."

Hollenbach doesn't disclose which Human leukocyte antigen (HLA) was mutated, but I think it may be HLA-B27. "HLA-B27 is a blood test to look for a protein that is found on the surface of white blood cells... (HLAs) are proteins that help the body's immune system tell the difference between its own cells and foreign, harmful substances. They are made from instructions by inherited genes."

While in our 20's, both my brother and I contracted Reiter's Syndrome. "Reactive arthritis, also called Reiter's syndrome, is the most common type of inflammatory polyarthritis in young men. It is sometimes the first manifestation of human immunodeficiency virus infection. An HLA-B27 genotype is a predisposing factor in over two thirds of patients with reactive arthritis."

https://www.aafp.org/pubs/afp/issues/1999/0801/p499.html#:~:text=Reactive%20arthritis%2C%20also%20called%20Reiter's,of%20patients%20with%20reactive%20arthritis.

I'm just trying to understand what lenz does. Why might it be an important drug in treating arthritis? More importantly, is a potential Big Pharma partner looking at lenz as a possible cure for arthritis?

Additionally, what does an arthritis drug have to do with treating coronaviruses, including mono? And the answer appears to be that both indications are associated with human immunodeficiency virus infection.

https://www.medrxiv.org/content/10.1101/2022.06.21.22276660v1

https://www.cdc.gov/epstein-barr/index.html

So I ask again, how many lenz patients have suffered breakthrough covid infections?