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Re: PJ007 post# 393203

Thursday, 09/15/2022 8:57:20 AM

Thursday, September 15, 2022 8:57:20 AM

Post# of 403225
This is something new. I believe this is the first reported study on a "non-enveloped" virus and again Brilacidin showed anti-viral activity. Non- Enveloped viruses could open a whole other world of treatments.

The in vitro evaluation of Brilacidin's antiviral activity was expanded to Echovirus, a non-enveloped picornavirus, to assess Brilacidin's effect on early viral entry in contrast to its ability to disrupt the lipid membranes of enveloped viruses. Brilacidin was shown to inhibit Echovirus, suggesting Brilacidin possesses additional antiviral mechanisms beyond its ability to directly impact viral envelopes.

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