High-dose (8mg) Eylea hits primary endpoints in AMD/DME: https://www.prnewswire.com/news-releases/aflibercept-8-mg-meets-primary-endpoints-in-two-global-pivotal-trials-for-dme-and-wamd-with-a-vast-majority-of-patients-maintained-on-12--and-16-week-dosing-intervals-301620404.html Whether these results are enough to materially cut into use of the coming Eylea biosimilars remains to be seen. I'm skeptical.