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jondoeuk

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jondoeuk

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Sunday, 08/28/2022 2:30:22 PM

Sunday, August 28, 2022 2:30:22 PM

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(OT) New preclinical data on ONKT102, an anti-CD38 CAR-NK cell product for R/R multiple myeloma https://www.onktherapeutics.com/wp/wp-content/uploads/2022/08/ONK-poster-IMS2022.pdf

It will have additional modifications, which are CISH knockout, and possibly a DR5-specific TRAIL variant. Also, they will add an (systemic) anti-IL-6R mAb https://www.sciencedirect.com/science/article/abs/pii/S1040842816301627 https://www.frontiersin.org/articles/10.3389/fendo.2018.00788/full
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