Oncternal Therapeutics Inc (ONCT)

[TechandBio]

Phase 3 with ABBV that makes their blockbuster drug Ibrutinib formerly pcyc which was bought out by ABBV for 20 billion this drug does 9 Billion in sales annually 50% more effective with less side effects. With ONCT Zilovertamab

R/R MCL: Tumor Reduction and Progression-Free Survival
Zilovertamab + Ibrutinib Data Update at ASCO 2022
85% ORR and median PFS of 35.9 months


ZILO-301: Phase III study of zilovertamab + ibrutinib vs ibrutinib in R/R MCL

ONCT 67 million dollar market cap today 20x-100x+ ROI potential here.

Chart looks primed for showtime!

Onct Leadership team is star studded.
https://oncternal.com/about/team

Thomas Kipps:
https://profiles.ucsd.edu/thomas.kipps
Thomas Kipps, MD, PhD, is Professor of Medicine, Evelyn and Edwin Tasch Chair in Cancer Research, and Deputy Director of Research Operations at the UC San Diego Moores Cancer Center. He received his Ph.D. in Immunology and M.D. from Harvard University and had his residency and fellowship training in Internal Medicine, Hematology, and Genetics at Stanford University.

Education and Training
Columbia College of Columbia University, New York, NY BS 1974 Biochemistry
Harvard Medical School, Boston, MA Ph.D. 1979 Immunology
Awards and Honors
UC San Diego School of Medicine 2004 Evelyn and Edwin Tasch Chair in Cancer Research


Dr. Kipps has a national and international reputation for his work in cancer research, immunology, and gene therapy. He has been a leader in the field for many years, and has helped to develop standardized treatment protocols. He is the author of more than 300 publications and is the PI on several peer-reviewed grants, including an award from NCI/NIH to fund the Chronic Lymphocytic Leukemia Research Consortium (CRC). The CRC involves collaboration with eight other Cancer Centers around the United States and the UK. Dr. Kipps is also the Director of the Blood Cancer Research Fund at the UC San Diego Moores Cancer Center. The Blood Cancer Research Fund concentrates on developing cures for all types of blood related cancers, specifically Chronic Lymphocytic Leukemia (CLL).

Non-canonical Wnt-Receptor Signaling and Targeted Therapies
NIH R01CA236361Apr 15, 2019 - Mar 31, 2024
Role: Principal Investigator
PCYC Karyotype
Pharmacyclics, Inc. Jun 1, 2018 - Dec 31, 2021
PCYC Clonal Evolution
Pharmacyclics, Inc. Feb 21, 2018 - Feb 20, 2021
Role: Principal Investigator
A Phase 1b/2a Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in B-Cell Cancers
California Institute for Regenerative Medicine (CIRM) CLIN2-10192Oct 1, 2017 - Jun 30, 2022
Role: Principal Investigator
Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies
California Institute for Regenerative Medicine (CIRM) TRAN1-10258Oct 1, 2017 - Mar 31, 2020
Role: Co-Investigator
Oncternal Research Agreement
Oncternal Therapeutics, Inc. Sep 1, 2016 - Aug 31, 2021
Role: Principal Investigator
Oncternal Therapeutics, Inc. HRPP #140141Apr 1, 2016 - Sep 26, 2018
Role: Principal Investigator
ROR1 Expression in Human Breast Cancer
Breast Cancer Research Foundation BCRF-18-123Oct 1, 2014 - Sep 30, 2019
Role: Co-Investigator
Protein-Coding and Non-Coding RNA Biomarkers for early detection of CLL
MD Anderson Texas R01CA182905Jun 1, 2014 - May 31, 2019
Role: Sub-Site Principal Investigator
Cancer Center Support Grant (CCSG)
NIH/NCI P30 CA23100-28May 1, 2014 - Apr 30, 2024
Role: Senior Deputy Director, Co-Principal Investigator
Specific Targets for Therapy of Patients with Chronic Lymphocytic Leukemia
The Leukemia & Lymphoma Society 7005-14Oct 1, 2013 - Sep 30, 2018
Role: Principal Investigator
Chronic Lymphocytic Leukemia Research Consortium
NIH/NCI 5P01CA081534-14Sep 24, 2012 - Aug 31, 2018
Role: Principal Investigator
Lenalidomide Treatment and the Chronic Lymphocytic Leukemia Microenvironment
NIH R21CA135681Mar 1, 2009 - Feb 28, 2011
Role: Principal Investigator
Center of Nanotechnology for Treatment, Understanding, *
NIH U54CA119335Sep 30, 2005 - Dec 31, 2011
Role: Co-Investigator
Chronic Lymphocytic Leukemia Research Consortium
NIH P01CA081534May 1, 1999 - Aug 31, 2018
Role: Principal Investigator
CHRONIC LYMPHOCYTIC LEUKEMIA RESEARCH CONSORTIUM
NIH P20CA081534May 1, 1999 - Apr 30, 2000
Role: Principal Investigator
MOLECULAR THERAPEUTICS OF RHEUMATOID ARTHRITIS
NIH/NIAMS P50AR044850Sep 28, 1998 - Aug 31, 2004
Role: Co-Investigator
ERB 2NEU DNA VACCINES FOR BREAST CANCER IMMUNOTHERAPY
NIH R01CA066000Sep 1, 1995 - Jun 30, 2003
Role: Principal Investigator
IMMUNOBIOLOGY OF AIDS LYMPHOMAS
NIH R01CA065408Jul 25, 1994 - Jun 30, 1998
Role: Principal Investigator
NEW MODALITIES FOR ACTIVE IMMUNOTHERAPY OF MALIGNANCIES
NIH R01CA057868Aug 25, 1992 - Jul 31, 1994
Role: Principal Investigator
NOVEL THERAPEUTIC APPROACHES IN HIV-ASSOCIATED LYMPHOMAS
NIH R01CA055513Jul 16, 1991 - Jun 30, 1994
Role: Principal Investigator
MECHANISMS OF AIDS-ASSOCIATED LYMPHOMAGENESIS
NIH R01CA054755Mar 14, 1991 - Feb 28, 1995
Role: Principal Investigator
Antibody V Gene Expression B Cell Lymphocytic Leukemia
NIH R37CA049870May 1, 1989 - Jul 31, 2015
Role: Principal Investigator
ANTIBODY V GENE EXPRESSION IN HUMAN B CELL MALIGNANCIES
NIH R01CA049870May 1, 1989 - Apr 30, 1994
Role: Principal Investigator
MULTIPARAMETER FLUORESCENCE ACTIVATED CELL SORTER
NIH S10RR004051Apr 18, 1988 - Apr 17, 1990
Role: Principal Investigator
MULTIPURPOSE ARTHRITIS CENTER
NIH P60AR033489Feb 1, 1987 - Jun 30, 1990
Role: Co-Investigator
HUMAN ANTIBODY DIVERSITY IN HEALTH &AUTOIMMUNITY
NIH R29AR038475Aug 1, 1986 - Jul 31, 1992
Role: Principal Investigator
IMMUNOLOGIC AGING AND AUTOIMMUNITY
NIH R01AG004100Jul 1, 1983 - Aug 31, 1996
Role: Principal Investigator
IMMUNOLOGIC AGING AND AUTOIMMUNITY
NIH R55AG004100Jul 1, 1983 - Aug 31, 1992
Role: Principal Investigator
Specialized Cancer Center Support Grant
NIH P30CA023100Apr 1, 1978 - Apr 30, 2024
Role: Principal Investigator
GENERAL CLINICAL RESEARCH CENTER
NIH M01RR000833Dec 1, 1977 - Sep 30, 2005
Role: Co-Investigator
General Clinical Research Center
NIH M01RR000827Mar 1, 1974 - Nov 30, 2010


Other Onct team comes from a variety of companies including Lily, Amgen, Roche, Johnson & Johnson, ISIS, Janseen, ABBV, Merck, Giliead and much much more. (Page 5)
https://investor.oncternal.com/static-files/f7628e1c-42c5-4c8a-8247-e910ad5555c4
Follow the breadcrumbs.

https://www.oncternal.com/pipeline


$ONCT