Humanigen Inc (HGENQ)

[DonDonDonDon]

i love his analogies including “ instead of turning off the sink faucets lenz turns off the water main”
and another “ lenz takes the foot off the accelerator and applies the brakes”

house is flooded , car ran off a cliff still accelerating.

what a bunch of bullshit that was

GM-CSF is responsible for the cytokine storm. The cytokine storm is responsible for severe Covid and death. Administering lenzilumab after a patient is already hypoxic isn't ideal. The cytokine storm is already on full blast. Once the cytokine storm is on full blast, there are already many other cytokines triggered. The LIVE-AIR trial had 720% efficacy on the primary endpoint for the patients with a CRP<41mg/L. That represented 25% of the patients in the trial. The ACTIV-5 trial might still have great data with those patients. It will be nice when Humanigen has that data to analyze. It will also be nice if they can do a trial for moderate patients. GM-CSF is upstream. Treating it early is obviously ideal.