SIGA Technologies Inc. (SIGA)

[axelvento]

Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection

"We show that initiation of antiviral treatment 24 h after lethal intratracheal MPXV infection, using either of the antiviral agents and applying various systemic treatment regimens, resulted in significantly reduced mortality and reduced numbers of cutaneous monkeypox lesions. In contrast, when monkeys were vaccinated 24 h after MPXV infection, using a standard human dose of a currently recommended smallpox vaccine (Elstree-RIVM), no significant reduction in mortality was observed."

https://www.nature.com/articles/nature04295?error=cookies_not_supported&code=8ba9329e-bf36-42ae-9d4b-f39a1411467f

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