Mind Medicine (MindMed) Inc (MNMD)

[DarthYoda]

United States Patent Application Publication Pub . No .: US 2022/0128580 A1
Inventors : Matthias E. LIECHTI , Oberwil ( CH ) ;
Urs Philipp DUTHALER , Basel ( CH )
Pub . Date : Apr. 28 , 2022

"METHOD OF QUANTIFYING LYSERGIC ACID DIETHYLAMIDE ( LSD ) AND
2,3 - DIHYDRO - 3 - HYDROXY - 2 - OXO LYSERGIDE ( O - H - LSD ) IN HUMAN PLASMA":

A method of measuring and identifying LSD and its major metabolite O - H - LSD , by obtaining a sample from an indi vidual , and measuring , identifying , and quantifying LSD
and O - H - LSD in the sample by performing a LC - MS / MS
analysis . A method of treating and monitoring individuals taking LSD , by administering a microdose of LSD , a prod
rug of LSD , or an analog of LSD to the individual , moni
toring the individual by obtaining a sample from an indi
vidual and measuring and identifying the analytes in the
sample by performing a LC - MS / MS analysis , and adjusting the microdose based on the amount of LSD quantified in the
LC - MS / MS analysis . A method of adjusting dosing of LSD , by administering a microdose of LSD , a prodrug of LSD , or
an analog of LSD to the individual , and adjusting the microdose based on blood concentration analytics

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