BIOS ended even worse: SPDR S&P Biotech ETF NYSEARCA: XBI Overview Compare Market Summary > SPDR S&P Biotech ETF 76.69 USD -4.88 (5.98%) Nasdaq Biotechnology Index XBI Last Updated: Apr 26, 2022 5:16 p.m. EDT 3,871.61 -145.97 -3.63%