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Monday, April 11, 2022 2:43:21 PM
The primary endpoint population of the ACTIV trial are patients with a CRP<150mg/L + <85yo + on remdesivir. That population had 243% efficacy in the LIVE-AIR trial on the primary endpoint. Stat sig in the ACTIV trial is a given on the primary endpoint. Stat sig on mortality is a real possibility. The LIVE-AIR had stat sig on mortality with the 336 patients with CRP<150mg/L and <85yo. There is still no effective treatment for newly hospitalized patients. Lenzilumab is a game-changer. Data will be our savior.
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