Genocea Biosciences Inc (GNCAQ)

[NY1972]

ICANS spans a variety of neurologic symptoms such as headache, tremor, speech impairment (e.g., expressive aphasia), delirium, confusion, impaired consciousness (stupor, lethargy, obtundation), and less commonly focal deficits. In our experience, delirum with preserved alertness was the most common presentation of ICANS, accounting for 66% of ICANS cases. In its most severe forms, ICANS can be associated with life-threatening features such as seizures and cerebral edema.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592274/