Humanigen Inc (HGENQ)

[DonDonDonDon]

Gabriel Hébert-Mild
https://twitter.com/Gab_H_R/status/1511707706096340993
Antibody-mediated SARS-CoV-2 uptake by monocytes/macrophages triggers inflammatory cell death that aborts production of infectious virus BUT causes systemic inflammation that contributes to COVID-19 pathogenesis
https://www.nature.com/articles/s41586-022-04702-4

Archimedes

Problem👆
Fix👇

Direct regulation of monocyte-macrophage activity by lenzilumab could provide a more favorable micro-environment where effector T cells could be protected from cytokine-induced apoptosis. This would preserve a non-exhausted Tcell phenotypehttps://t.co/nnuZOeR26y

— Archimedes (@AlphaTrader00) April 6, 2022

Direct regulation of monocyte-macrophage activity by lenzilumab could provide a more favorable micro-environment where effector T cells could be protected from cytokine-induced apoptosis. This would preserve a non-exhausted Tcell phenotype
https://www.mayoclinicproceedings.org/article/S0025-6196(21)00006-9/pdf