Friday, April 01, 2022 10:41:21 PM
It is not. When the science actually supports the drug like it does with lenzilumab, an authorization is completely possible. Maybe the pump and dumps make it seem virtually impossible if you are not paying attention to the actual science. But Humanigen is not a pump and dump. Double blind, placebo controlled, clinical trials are just and fair. Thank god for science. The ACTIV-5 will vindicate. Clearly, lenz came close to the EUA in September. And with the 336 out of 479 patients in the LIVE-AIR who had a CRP<150mg/L+<85yo, 6.6% died in the lenz arm and 13.8% died in the placebo arm. That is loco data. No other treatment for hospitalized patients comes close. There is still no authorized treatment for newly hospitalized patients. None. And patients with a CRP<150mg/L+<85yo is the primary endpoint population of the ACTIV-5 trial. In other words, the ACTIV-5 trial will clearly have stat sig on mortality and obviously stat sig with the primary endpoint. GM-CSF is the master controller of the cytokine storm. It is the cytokine that begins the cytokine storm. One ring to rule them all.
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