Relief Therapeutics Holding AG (RLFTF)

[changes_iv]

CDC on Alzheimer’s —-Key Facts

Alzheimer’s disease is not a normal part of aging.

6.2 million Americans are estimated to be living with Alzheimer’s disease in 2021.

Symptoms usually begin after age 60, but Alzheimer’s disease likely starts a decade or more before problems first appear.

Risk factors include aging, diabetes, high blood pressure (hypertension), smoking cigarettes, and a family history of dementia.

Alzheimer’s death rates increased 33% from 1999 to 2019.

An estimated two-thirds of those who die of dementia do so in nursing homes, compared with 20% of people with cancer and 28% of people dying from all other conditions

In 2020, more than 11 million Americans provided an estimated 15.3 billion hours of unpaid care, a contribution to the nation valued at $257 billion.

Currently, there is no cure. There are pharmaceutical and behavioral interventions for managing symptoms.

Persons with dementia, their families and caregivers can benefit from care planning.

https://www.cdc.gov/dotw/alzheimers/index.html

VIP injected intracerebroventricularly or delivered intranasally prevented impairments in spatial learning and memory associated with cholinergic blockade. These studies suggest both an unusual therapeutic strategy for treatment of Alzheimer deficiencies and a means for noninvasive peptide administration to the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC40251/

“Aviptadil is a drug that mimics vasoactive intestinal polypeptide (VIP), however, with prolonged effects, compared to the endogenous (produced by the body) VIP,” he said.

“VIP and aviptadil act in a type of lung cell called alveolar type II (AT-2), that, although representing just as few as 5% of the cells in the lungs, are largely responsible for oxygen transfer and inhibition of dysfunctional hyper inflammatory reaction and cytokine storm, through the inhibition of the activity of one of the main triggers of these reactions, called NMDA-induced caspase-3.”

Dr. Cadegiani noted that “to date, there is no other molecule capable of working at late stage against COVID-19, and at the same not causing immunosuppression.”

He also believes aviptadil blocks the IL-6, the most dangerous cytokine at the center of the pulmonary dysfunction related to COVID-19. “The importance is that IL-6 is the cytokine that is not effectively blocked by glucocorticoids, even in very high doses. Thus, aviptadil/VIP could confer additional protection when we most need and when we have the fewest resources for.”

He went further to suggest that it is downright malpractice for hospitals not to try this drug at late stage, given the absence of alternatives. “Due to the absence of therapeutic alternatives targeting AT-2 and IL-6, and given the already well-established safety profile, its approval goes beyond the attempt-to-try principle, since it is highly plausible and likely that it works. Therefore, instead of an action of attempt-to-try when giving aviptadil, not providing it when patients fail to respond to other therapies can be considered a medical negligence, from a bioethical perspective.”

https://amgreatness.com/2022/03/09/in-letter-to-fda-and-niaid-ron-johnson-demands-to-know-why-promising-late-stage-covid-drug-was-never-approved/

Vaccine: Micro Blood Clots in D-dimer tests??

https://rumble.com/vv70q7-emergency-medicine-doctor-shows-micro-blood-clots-in-d-dimer-tests.html

Consequences??

https://rumble.com/vyddo9-cruz-asked-if-hell-vote-for-ketanji-brown-jackson.-he-answers-bluntly..html

Consequences??

https://rumble.com/vyi2nc-ketanji-brown-jackson-implies-old-laws-are-unfair-for-some-sex-offenders.html

Consequences??

https://rumble.com/vnhb19-where-are-the-feds-sending-the-illegals-todd-bensman-with-sebastian-gorka-o.html

Consequences??

https://rumble.com/vwdzx3-republican-opponent-to-ilhan-omar-drops-new-ad-and-its-devastating.html

Consequences??

https://rumble.com/vnjaul-trump-tears-into-ilhan-omar-she-married-her-own-brother.html

Consequences??

https://rumble.com/vvktu6-royce-white-for-congress..html

Consequences??

https://rumble.com/vy8vih-steve-bannon-gives-royce-white-a-shoutout.html

Consequences??

https://rumble.com/vyjtws-biden-tells-us-troops-theyre-going-to-ukraine-white-house-panics.html

Consequences??

https://rumble.com/vyfs4r-victor-davis-hanson-on-why-the-architect-of-globalism-larry-fink-is-changin.html