Politics and Money

[lesgetrich]

Let me help you. Perhaps you have a litter of what's called hermaphrodites. It's a natural condition that appears in both animals and humans where the individual has both male and female sex organs. I guess this must freak you out you poor dear. It must just be too much for your poor little brain to comprehend. There's a nice explanation on Wikepedia that even has pictures for those who are intellectually challenged...

True hermaphroditism

On the other hand, it might just make you aware that humans are not always born all male or all female. Nature can be wonderous that way...

How genes and evolution shape gender – and transgender – identity

Mismatch between biological sex and gender identity, culminating in its severest form as gender dysphoria, has been ascribed to mental disease, family dysfunction and childhood trauma.

But accumulating evidence now implies biological factors in establishing gender identity, and a role for particular genes.

Variants – subtly different versions – of genes linked with gender identity might simply be part of a spectrum of gender and sexuality maintained throughout human history.

Transgender and gender dysphoria

Some young boys show an early preference for dressing and behaving as girls; some young girls are convinced they should be boys.

This apparent mismatch of biological sex and gender identity can lead to severe gender dysphoria. Coupled with school bullying and family rejection, it can make lives a torment for young people, and the rate of suicide is frighteningly high.

As they move into adulthood, nearly half of these children (or even more when the studies are closely interrogated), continue to feel strongly that they were born in the wrong body. Many seek treatment – hormones and surgery – to transition into the sex with which they identify.

Although male to female (MtF) and female to male (FtM) transitions are now much more available and accepted, the road to transition is still fraught with uncertainty and opprobrium.

Transwomen (born male) and transmen (born female) have been a part of society in every culture at every time. Their frequency and visibility is a function of societal mores, and in most societies they have suffered discrimination or worse.

This discrimination stems from a persistent attitude that transgender identification is an aberration of normal sexual development, perhaps exacerbated by events such as trauma or illness.

However, over the last decades, growing recognition emerged that transgender feelings start very early and are very consistent – pointing to a biological basis.

This led to many searches for biological signatures of transsexualism, including reports of differences in sex hormones and claims of brain differences....

A recent and much larger study assembled samples from 380 transwomen who had, or planned, sex change operations. They looked in fine detail at 12 of the “usual suspects” – genes involved in hormone pathways. They found that transwomen had a high frequency of particular DNA variants of four genes that would alter sex hormone signalling while they had been developing in utero.

There may be many other genes that contribute to a feminine or a masculine sexual identity. They are not necessarily all concerned with sex hormone signalling – some may affect brain function and behaviour.

The next step in exploring this further would be to compare whole genome sequences of cis- and transsexual people. Whole genome epigenetic analyses, looking at the molecules that affect how genes function in the body, might also pick up differences in the action of genes.

It’s probable that many – maybe hundreds – of genes work together to produce a great range of sexual identities.

How would “sexual identity genes” work in transgender?
Sexual identity genes don’t have to be on sex chromosomes. So they will not necessarily be “in sync” with having a Y chromosome and an SRY gene. This is in line with observations that gender identity is separable from biological sex.

This means that among both sexes we would expect a spread of more feminine and more masculine identity. That is to say, in the general population of males you would expect to see a range of identities from strongly masculine to more feminine. And among females in the population you would see a range from strongly feminine to more masculine identities. This would be expected to produce transwomen at one end of the distribution, and transmen at the other.

This occurrence of a range of differing identities would be comparable with a trait such as height. Although men are about 14 cm taller than women on average, it’s perfectly normal to see short men and tall women. It’s just part of the normal distribution of a certain human characteristic expressed differently in men and women.

This argument is similar to that which I previously described for so-called “gay genes”. I suggested same–sex attraction can readily be explained by many “male-loving” and “female-loving” variants of mate choice genes that are inherited independently of sex.

BTW You might also find this article interesting. It's written in simple English even you can understand...

Mythbuster: Debunking Anti-Transgender Messages