Tuesday, January 25, 2022 10:39:33 PM
Immix Biopharma Inc's (NASDAQ: IMMX) IMX-110 + anti-PD-1 produced 63-day median survival in a genetic pancreatic cancer mouse model, in which mice develop their own pancreatic cancer and have an intact immune system.
Historically, 42-days is the median survival produced by a 4-drug combination: 2 chemotherapies and two immunotherapies in the same genetic pancreatic cancer mouse model.
"This data highlights why we are excited to collaborate with BeiGene on our planned 2022 Phase 1b/2a combination trial of IMX-110 + BeiGene anti-PD-1 tislelizumab in advanced solid tumors," said Ilya Rachman, CEO of ImmixBio. "We believe this upcoming combination clinical trial will allow us to expand into multiple oncology indications rapidly."
In 2022, the Company plans to commence combination IMX-110 + BeiGene Ltd (NASDAQ: BGNE) anti-PD-1 tislelizumab Phase 1b/2a clinical trial in advanced solid tumors.
Related: Immix's Lead Program Shows 50% Response Rate In Resistant Cancer In Animal Study.
The FDA has approved orphan drug designation for IMX-110 for soft tissue sarcoma. Additionally, the FDA has approved rare pediatric disease designation to IMX-110 for rhabdomyosarcoma.
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