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Sunday, 01/16/2022 9:53:37 AM

Sunday, January 16, 2022 9:53:37 AM

Post# of 892
I'm encouraged to believe our presentations at ASCO's fast approaching symposium will certainly bring us, and keep us well over a $buck.

American Society of Cancet Oncologists' (ASCO's) symposiums introduce and update therapeutic developments.

We've been introduced and progress noted in admittedly small clinical trials..Trial data for both our Sarcoma and Pancreatic are due.
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Here's the MPS drug regimine concurrent with SM-88


trial(s) ,,,, designed to evaluate the safety and efficacy of SM-88 used with MPS (methoxsalen (1), phenytoin(2) and sirolimus) in pancreatic cancer and will measure multiple endpoints, including overall survival, progression free survival, relevant biomarkers, quality of life, safety, and overall response rate.

…..(1) Methoxsalen - used with UV light on skin to prevent severe psoriasis
…..(2) Phenytoin - Anti-seizure and –convulsant used to control certain type of seizures, and to treat and prevent seizures that may begin during or after surgery to the brain or nervous system. Phenytoin is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain
….(3) Sirolimus - immuno suppressants
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This year's ASCO shindig Annie excerpt

TYME Technologies, Inc. (Nasdaq: …... Oral SM-88 plus MPS, an effective yet less toxic treatment option in second-line advanced pancreatic cancer.
Final phase II/III study results, has been accepted for poster presentation at the 2022 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, January 20 – 22, 2022, in San Francisco, CA.
________________________Excerpts from Last Year's cocktail party :)

Journal of Clinical Oncology - published online before print January 22, 2021

Phase II/III Study of SM-88 in Patients with Metastatic Pancreatic Cancer.

Randomized and evaluable subjects (n=38) included mean age 65y (45-86);
BMI 24.6 (18.8-38.7); female 39.5%; White 76.3%. Of treated subjects 65.8% (25/38) had 166 AEs, with 25.7% (26/101) being at least possibly SM-88-related
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