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Re: None

Saturday, 02/03/2007 1:00:13 AM

Saturday, February 03, 2007 1:00:13 AM

Post# of 40
Someone who has been down this path before. The ph ii is written up below (and also in JAMA)

http://www.medscape.com/viewarticle/464397

Note that despite the fact that this trial showed a very good result in CKMB and in previous related trials it failed in subsequent, larger, trials.

Other notes - For the above trial the definition of MI is not as simple as CKMB>x although that was one component.

It would be interesting to know whether the drug lowered CKMB in the failed trials - as a measure of how tightly CKMB is coupled with MI/Death.