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Thursday, December 30, 2021 9:37:32 AM
lenzilumab is by far the best drug not yet approved
Lenz might be the best Covid drug period. And it treats newly hospitalized patients. There are literally zero effective drugs currently authorized for newly hospitalized patients.
The ACTIV-5 trial will prove lenz's worth. The primary endpoint in the ACTIV-5 is for patients with CRP<150mg/L and <85yo. That group represented 336 of 479 patients in the LIVE-AIR trial. That group had 196% efficacy in the LIVE-AIR trial for a p value of 0.0003. That efficacy will be replicated in the ACTIV-5 because GM-CSF is the key to treating Covid.
https://www.bbc.com/news/health-56352128
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