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Post# of 252589
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Alias Born 03/18/2005

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Thursday, 02/01/2007 7:49:24 PM

Thursday, February 01, 2007 7:49:24 PM

Post# of 252589
Expert prediction of clinical program outcomes

Hello! I'm interested in hearing everyone's thoughts and starting a conversation to investigate the following question: To what extent can a clinical program's success or failure be predicted using knowledge of drug mode-of-action, published research, clinical endpoints, etc.etc. I've gone back through these boards and elsewhere after some high-profile misses (Nuvelo with Alfimeprase, Pfizer with Torcetrapib) and found some skepticism about those programs. I know I may be asking a biased crowd (I don't think we'd be here if we thought it was a crapshoot). Does anyone have insights they'd like to share about the process? What are the limitations? How do you maximize predictive power? Any tips for doing research?

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