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Friday, 11/26/2021 5:43:01 PM

Friday, November 26, 2021 5:43:01 PM

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Merck needs CYDY- From today’s NYT

The pharmaceutical company Merck said on Friday that in a final analysis of a clinical trial, its antiviral pill reduced the risk of hospitalization and death among high-risk Covid patients by 30 percent, down from an earlier estimate of 50 percent.
The lower efficacy is a disappointment for the drug, known as molnupiravir, which health officials around the world are counting on as a critical tool to save lives and reduce the burden on hospitals. It increases the importance of a similar, apparently more effective, offering from Pfizer that is also under review by the Food and Drug Administration.
A panel of advisers to the F.D.A. is set to meet on Tuesday to discuss Merck’s treatment and vote on whether to recommend authorizing it to treat high-risk Covid patients.
In briefing documents posted to the F.D.A.’s website on Friday, agency reviewers did not take a position on whether the drug should be authorized, though they found that the clinical trial data did not show any major safety concerns and that the drug was effective in preventing severe disease.
The reviewers said they had only become aware of the updated efficacy estimate earlier this week and were still reviewing the data. They said they could update their assessment when the panel meets on Tuesday.
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