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Thursday, 11/18/2021 3:47:30 PM

Thursday, November 18, 2021 3:47:30 PM

Post# of 44377
The question has arisen as to the prudence of Curative pursing the use of IMT504 in the development of a COVID19 vaccine. The following sheds some insight into this strategic move.

“It is becoming increasingly clear that the initial COVID-19 vaccines developed are not working for everyone. There are highly vulnerable people, such as those patients with kidney failure who require kidney transplantation or dialysis, who are being left behind. We need targeted vaccines for this immunocompromised patient group," said Curative Biotech Chairman & President Paul Michaels.

Curative Biotech and Mid-Atlantic BioTherapeutics have agreed to develop a next generation COVID-19 vaccine targeted to meet the needs of this vulnerable population. A consequence of kidney failure in general is the loss of a robust immunologic response to infections, including COVID-19. This means that kidney failure patients may get a more severe version of COVID-19 that could lead to a greater chance of hospitalization or even death.

Dr. David Horn, CEO of Mid-Atlantic BioTherapeutics, added: "It is well known that kidney transplant recipients have impaired responses to mRNA COVID-19 vaccines. Recent data from France reveals that, even after 4 vaccine shots, many kidney transplant recipients have poor responses. In addition, kidney failure patients on dialysis do not initially respond as well to current vaccines and rapidly lose measurable antibodies when compared to the general population."

This solution to the best of my knowledge could be advanced under Operation Warp Speed. Operation Warp Speed was a public–private partnership initiated by the United States government to facilitate and accelerate the development, manufacturing, and distribution of COVID-19 vaccines, therapeutics, and diagnostics. In short, there is a potential expedited path forward for this COVID-19 vaccine solution, which is currently not being addressed by big pharma.

What better person to have as an advisor on this and the other initiatives than Dr. Catherine Sohn?

Again, here is a link to Dr. Sohn’s bio…

https://axcellatx.com/team/catherine-a-sohn-pharm-d/