We know activity to TIL, anti-PD-1, anti-PD-L1 and anti-CTLA-4 is due to neoantigen-reactive T-cells. Also, NSCLC patients with a high clonal neoantigen burden have improved disease free survival (based on data from the TRACERx consortium). However, doses and percentage of reactive T-cells in the product matter. So it won't be at least until next year that we might start to see patients respond (due to them giving higher doses).
Yes, but it could drop (slightly) when data are presented at SITC.
Recent ACHL News
- Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16] • Edgar (US Regulatory) • 09/19/2024 11:17:25 AM
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- Form 144 - Report of proposed sale of securities • Edgar (US Regulatory) • 02/01/2024 06:14:13 PM
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- Achilles Therapeutics Receives Nasdaq Deficiency Notice Regarding Minimum Bid Price Requirement • GlobeNewswire Inc. • 09/22/2023 08:30:00 PM
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