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Re: runncoach post# 18396

Tuesday, 10/19/2021 10:08:24 AM

Tuesday, October 19, 2021 10:08:24 AM

Post# of 21540
Worth mentioning is that bryo fixes this problem upstream and that this is just one of its benefits.

https://pubmed.ncbi.nlm.nih.gov/22700373/

"Activation of the a-secretase processing pathway of amyloid precursor protein (APP) is recognized as an important mechanism which diverts APP processing from production of beta-amyloid (Aß) to non toxic sAPPa, decreasing Alzheimer's disease (AD) plaque formation and AD-associated cognitive deficits."

"Because bryostatin-1 is a highly potent PKC-d and -e activator which activates a-secretase APP processing, further characterization of bryostatin-1/bryologues may help refine their use as important tools for the clinical management of AD."
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