Relief Therapeutics Holding AG (RLFTF)

[changes_iv]

MYOCARDITIS???

Inflammation of the middle layer of the heart wall.

Myocarditis is usually caused by a viral infection. A severe case can weaken the heart, which can lead to heart failure, abnormal heartbeat, and sudden death.

PERICARDITIS???

A swelling and irritation of the thin saclike membrane surrounding the heart (pericardium).

Pericarditis may be caused by a viral infection or heart attack. In many cases, the cause is unknown.

~ MAYO CLINIC


Myocardial fibrosis is defined by a significant increase in the collagen volume of myocardial tissue. It is a complex process that involves all components of the myocardial tissue and can be triggered by tissue injury from myocardial ischemia (hypoxia), inflammation, and hypertensive overload.

~ Mayo Clinic Proceedings

We conclude that VIP [Vasoactive Intestinal Peptide] infusion increased myocardial VIP concentration and was able to reverse existing myocardial fibrosis suggesting a possible therapeutic role for a VIP based therapy in cardiac failure.

https://pubmed.ncbi.nlm.nih.gov/31449808/