Humanigen Inc (fka HGENQ)

[CJames22]

It is designed to be variant agnostic. It's a nucleoside analog that disrupts viral replication. The RNA polymerase recognizes it, incorporates it, and this causes a disruption of the RNA replication and a mess of downstream errors that prevents successful replication (I'm not super well versed in it's mechanism but I believe this is the gist).

It's possible for a strain to mutate and develop ways to evade this drug I'm sure but this will have good, broad coverage of all COVID strains.

The delta variant replicates much faster and viral loads are much greater compared to wild type strain, though, so that might change how effective MRK's drug is. I'm interested to see the complete data from the study