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Friday, October 01, 2021 6:35:10 AM
The Merck trial is a Phase III study.
Also note the sample size:
"At the time of the decision to stop recruitment based on the compelling interim efficacy results, the trial was approaching full recruitment of the Phase 3 sample size of 1,550 patients, with more than 90% of the intended sample size already enrolled."
I still maintain that even with a sicker cohort (which as some longs have noted may be a disadvantage rather than an advantage) in the brilacidin study, 120 patients is not enough to show a statistically significant difference versus placebo, and even if it does, that will not be sufficient to gain an EUA.
https://www.merck.com/news/merck-and-ridgebacks-investigational-oral-antiviral-molnupiravir-reduced-the-risk-of-hospitalization-or-death-by-approximately-50-percent-compared-to-placebo-for-patients-with-mild-or-moderat/
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