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Re: oddone33320 post# 376737

Thursday, 09/30/2021 2:45:57 PM

Thursday, September 30, 2021 2:45:57 PM

Post# of 402958
The trial isn't including people on ventilators at the time of dosing:

See the trial exclusion criteria:

Requiring invasive mechanical ventilation and/or extracorporeal membrane oxygenation (ECMO) at the time of randomization.

The Compassionate Use patients already ran the SOC course AND were on ventilation for days before getting Brilacidin.

I'm not seeing the problem with the endpoint. Ideally Brilacidin keeps our trial participants off the ventilator or gets them off after a brief stint.

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