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Re: sunspotter post# 376580

Wednesday, 09/29/2021 3:33:27 PM

Wednesday, September 29, 2021 3:33:27 PM

Post# of 403528
For me this publication speaks about using nanoparticles together with antibiotics to make bacteria more susceptible to destruction. If I understand well, they say a reason for drug resistance is a *efflux pump system* in the bacteria. It is maybe not correct but I imagine a wee pump in the bad bacteria that can expel or reject a drug that is supposed to kill it. *The major cause of resistance to date is the efflux system, which makes the latest generation of antibiotics ineffective without reaching the target site. If species-specific nanomaterials are used to control the activity of efflux pumps, it could revolutionize the field of medicine and make the previous generation resistant medications active once again.*

Brilacidin is a new antibiotic that demonstrated in trial it can kill drug-resistant MRSA bacteria quickly. If there is new technology that can help Brilacidin work even better I would be happy to learn more on this. And Google says that Brilacidin is mentioned in this publication.

Maybe it is nothing like Mr. KMBJN says. But if you can access this publication I would appreciate to have a look.
Thank you.
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