Bionanao Genomics Inc (BNGO): Lots of volume and now price increase on...

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Friday, 09/17/2021 1:15:39 PM

Friday, September 17, 2021 1:15:39 PM

Lots of volume and now price increase on the Great News from yesterday!

Bionano Genomics Announces Study Finds The Combination Of Optical Genome Mapping And Short-Read Sequencing Provides A Comprehensive Genome Analysis For Lung Cancer Samples And Enables The Discovery Of New Biomarkers

Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer-related death worldwide. Genomic structural variations (SVs), including large indels, inversions, duplications, and translocations, are essential causes of alterations in gene expression and are recognized as hallmarks in tumorigenesis. In this study, recurrently SV-disrupted genes were significantly enriched in cancer-related pathways highlighting the importance of OGM for detecting all classes of SVs. This study utilized short-read NGS and Bionano's OGM to obtain high-technical-confidence somatic SVs to investigate candidate oncogenes in cancer patients. An essential role of high-technical-confidence somatic SVs guided the identification of two new oncogenes (TRIO and SESTD1) in NSCLC.

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