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Monday, September 06, 2021 7:29:59 PM
https://www.genengnews.com/covid-19-candidates/relief-therapeutics/
NRx Pharmaceuticals has reported additional data from Phase IIb/III clinical trial where its drug, Zyesami (aviptadil), offered a rise in blood oxygen within a day in critical Covid-19 patients with acute respiratory failure.
Zyesami is a synthetic form of vasoactive intestinal polypeptide (VIP), which attaches selectively to the alveolar type II cell (ATII) in the air sac (alveolus) of the lung.
The latest analysis results showed that subjects receiving Zyesami had improvement in blood oxygen, which signifies improved lung function, within a day of commencing therapy.
…
“The benefit was seen across all patients, all baseline severities, and all types of hospitals.
“We believe this new finding illustrates Zyesami’s mechanism of action in a placebo-controlled trial and supports our application for breakthrough therapy designation to the FDA.”
https://www.pharmaceutical-technology.com/news/nrx-zyesami-covid-trial/
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