Thursday, September 02, 2021 1:46:18 PM
"It has been found that 40% of patients with COVID-19 develop ARDS, and 20% of ARDS cases are severe. The prevalence of post-COVID-19 fibrosis will become apparent with time, but early analysis from patients with COVID-19 on hospital discharge suggests that more than a third of recovered patients develop fibrotic abnormalities. The pathological feature of ARDS is diffuse alveolar damage (DAD) which is characterized by an initial acute inflammatory exudative phase with hyaline membranes, followed by an organizing phase and fibrotic phase. Previous studies highlight that duration of disease is an important determinant for lung fibrosis post ARDS. This study showed that, 4% of patients with a disease duration of less than 1 week, 24% of patients with a disease duration of between weeks 1 and 3, and 61% of patients with a disease duration of greater than 3 weeks, developed fibrosis."
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