Innovation Pharmaceuticals Inc (IPIX)

[Bad_Timing]

Some wishful thinking while we wring our hands waiting for results.

This finding suggests that all tested cancer cells are negatively-charged and normal cells are either charge-neutral or slightly positive (Le et al., 2020).

Indeed, cationic AMPs are able to disrupt microbial cell membranes by interacting with negatively charged phospholipids. Moreover, several peptides are capable to trigger cytotoxicity of human cancer cells by binding to negatively charged phosphatidylserine moieties which are selectively exposed on the outer surface of cancer cell plasma membranes (Tornesello et al., 2020).

Brilacidin is a biomimetic polymer that captures the structural and biological properties of HDP's. - company slide decks

While we don't have a pivotal Phase III yet, through the multiple Phase II's for a ranges of antibiotic, anti-inflammatory, and immunomodulating applications, evidence is building that B does indeed work like a synthetic version of an AMP. What if the same MoA extends to cancer? How much is B worth then?