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Re: thefamilyman post# 368065

Friday, 07/30/2021 11:18:14 AM

Friday, July 30, 2021 11:18:14 AM

Post# of 403397
"In other words, Brilacidin is NOT a compound that would fail in a clinical setting due to it causing phospholipidosis because it has already been through multiple clinical trials and has NOT failed."


I do wish people would actually read my post and the associated article and try to understand them rather than construct a straw man of their own choosing and then rather pointlessly beat it to death.

Again, I'm not suggesting brilacidin causes phospholipidosis in the clinical setting - quite the opposite.

The point is that if the anti-coronavirus success of brilacidin in vitro is due to an in vitro phospholipidosis effect - and it plausibly could be as anyone who has read Dr. DeGrado's papers on MoA will realise - then as it doesn't seem to cause phospholipidosis in the doses used, it's unlikely to work as an anti-viral in humans.

The fcat that it appears to have worked in Phase II studies as an anti-bacterial, anti-modulatory or anti-inflammation agent is not relevant to its action as an antiviral.

Please see the original post:

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=165164398



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