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Re: A deleted message

Monday, 07/19/2021 10:54:12 PM

Monday, July 19, 2021 10:54:12 PM

Post# of 232887
If Cytodyn says 300% increase in "mean PFS" and 450% increase in overall survival in 12 months, how can we possibly say those survival numbers are not better than typical medians? The PR has not given any information on the actual median PFS in either arm of this study, so how can we compare with some data elsewhere (of "typical medians")?

It would make more sense to understand that when our data for mPFS or OS for the LL arm is compared against the Placebo arm, we find that the mPFS for LL arm is 300% higher than placebo arm (like 4 months vs 1 month) and 450% higher for OS (like 11 patients survived vs 2).

(4-1)/1 = 3 (4 is 300% increase over 1)
(11-2)/2 = 4.5 (11 is 450% increase over 2)
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