Innovation Pharmaceuticals Inc (IPIX)

[Justfactsmam]

Completely False:

The majority of the few hundred patients treated with brilacidin so far experienced adverse events, some of them serious.

If brilacidin ever gets used in a few thousand patients, then we'll have a better idea of its safety profile, but it doesn't look good so far.

In the meantime there's no Phase III data to show it even works.

Reviewing this commentary:

"The majority of the few hundred patients treated with brilacidin so far experienced adverse events, some of them serious."

... Some "tingling" in "some" patients, not a majority...could be recategorized (misrepresented) as an "adverse event" which was resolved promptly AND there was NO conclusive evidence that "some" blood pressure issues deemed "SAE"...and where occurred it was resolved almost immediately with meds. NO SAE TIED TO BRILACIDIN. (muddies up the water)

"If brilacidin ever gets used in a few thousand patients, then we'll have a better idea of its safety profile, but it doesn't look good so far."

... Always get a "better idea" with more patients...but you ABSENT FORM THE STATEMENT ...BRILACIDIN/COVID TRIALS ARE FOR PHASE II..."EFFICACY".

IN FACT BRILACIDIN SKIPPED PHASE I "SAFETY" because BRILACIDIN HAD ALREADY PASSED SAFETY HURDLE ... and ALSO DID SO WITH and AFTER ABSSSI TRIALS...

"In the meantime, there's no Phase III data to show it even works."

Referencing "no Phase III" to show that it works...OBVIOUS OBSERVATION... BUT...also another OBVIOUS OBSERVATION ik that IPIX/BRILACIDIN IS IN PHASE II, and was just completed...IT IS AN "EFFICACY STUDY"...and will of course reflect more safety data...but it is PRIMARILY EFFICACY...from which EUA could be granted! Phase III could be done concurrently with the EUA administration.


PS A high-profile Brooklyn hospital administrator has stated to me that numerous serious liver complications have developed in patients to whom Remdesivir was administered. NO FORMAL REPORTING has taken place to CDC, since reporting is on a "voluntary" basis, patient to patient...
Nice way to hide a very SAE, for the time being...but that NEWS will eventually come out. The thought process was "pick your poison"...better to risk damaging the liver than let the patient potentially die. Thank you Dr. Fauci...

IMO if BRILACIDIN DOES NOT DEMONSTRATE SAE...i.e. liver damage ... and meets its minimum goals...it will be deemed a HUGE THERAPEUTIC SUCCESS.

PPS. While we wait for Trial Results...As Per PR...UC Trials appear to be on the runway...IMO could be multiple BP watching and influencing the protocol for those trials UC and Crohn's definite unmet need. A potential BLOCKBUSTER with IMO BP all over it.