Saturday, June 26, 2021 1:25:56 AM
Avexis was a vector gene therapy company using AAV9 with 15 successfully treated human SMA babies, a few very early other MD vectors, and some preliminary CAR-T work. An inferior technology IMO with some questions of durability and long term safety. Novartis snatched them up for $8.7B.
https://www.fiercebiotech.com/biotech/novartis-inks-8-7b-avexis-buyout-to-build-gene-therapy-unit
Spark was a gene therapy company with a host of genetic eye disease vector gene therapies on market and in development with very limited revenuee from these conditions. Roche bought them for $4.3B.
https://www.fiercepharma.com/pharma/roche-to-wrap-up-4-3b-spark-deal-after-antitrust-ordeal-ends-ftc-thumbs-up
Astellas with early vector company Audentes $3B. https://www.fiercebiotech.com/biotech/astellas-inks-3b-audentes-buyout-to-expand-gene-therapy
All inferior technology for many reasons…Eli Lilly already thinks our first six genes are worth $2.6B plus royalties on sales. What is the whole platform and CAR-T program worth?
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