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Re: PlanTrader post# 38788

Tuesday, 06/15/2021 9:44:06 AM

Tuesday, June 15, 2021 9:44:06 AM

Post# of 43716
Plan trader

a high incidence of drop-outs due to MK having reduced the tumor so much that they don't want to go through the brutal SOC? Thereby making them disqualified for the study's primary endpoint even though that is a HUGE success facto



It does not work this way because we are in and Intent to Treat (ITT) design, eg all those randomized are counted for in each arm, whether they take the treatment totally or partially.

The only reason those patients wouldn't be included would be if they disappeared without leaving a trace.
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