Humanigen Inc (fka HGENQ)

[DonDonDonDon]

Can a double blind trial for a drug take place if the same drug already has an EUA for the same indications?

I think the EUA would end all placebo controlled trials at least in the US. A phase 4 trial would then start after the EUA is granted where there are no placebo patients. Since leronlimab's regular trial didn't have stat sig on mortality maybe they want a more robust ACTIV trial so that stat sig on mortality can be obtained.