Wednesday, June 09, 2021 5:52:39 PM
Also a couple of 'significant' quotes from recent PRs to go along with the Ifenprodil/stroke "nugget" you found.
https://pubchem.ncbi.nlm.nih.gov/compound/Ifenprodil
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The Company has decided to expand its clinical investigation of Ifenprodil based on the drug’s significant effectiveness in treating a number of diseases including cancers, chronic disorders and psychological disorders such as addiction and PTSD, in certain pre-clinical and clinical studies. Algernon also recently announced that Ifenprodil, in its multi-national COVID-19 study, significantly reduced interleukin 6 (IL-6) at day five in the 20mg treatment arm, compared to the standard of care group. IL-6 is a pro-inflammatory cytokine and its involvement in multiple disease indications has been well established, including PC where its over-expression is related to poor survival.
https://www.globenewswire.com/news-release/2021/06/03/2241141/0/en/Algernon-Pharmaceuticals-Launches-Pancreatic-Cancer-Clinical-Research-Program-with-Ifenprodil.html
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The animal study from the University of Szeged in Hungary showed that DMT reduced the activity of some of the mechanisms and effects that are involved in the damaging biological cascade that occurs after a stroke. In addition, DMT, reduced the volume of dead cells and increased the viability of cells found in the somatosensory cortex, all with statistical significance. One of the study’s authors is Dr. Ede Frecska who recently joined Algernon as a consultant to its DMT stroke program.
https://www.globenewswire.com/news-release/2021/05/27/2237256/0/en/Algernon-Pharmaceuticals-Highlights-New-Animal-Study-Showing-Effectiveness-of-Psychedelic-Drug-DMT-in-Treatment-of-Stroke.html
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