Humanigen Inc (fka HGENQ)

[DonDonDonDon]

How many doses does a patient need?
At what point in the disease development exactly does the administering 'optimally' need to be done. Earlier in the time-lines = more doses needed because they will be administered preventively to a larger number of people that in the end (with hindsight) wouldn't have needed them.

When they say 100k doses, they mean 100k treatments of 1,800mg. But I do think you have a point that things will change. Lenzilumab's trial has awesome efficacy on its first try. Efficacy will go even higher when they learn how to better administer it. I personally believe that they will eventually use lenzilumab on moderate and even mild patients. GM-CSF levels are elevated in the early stages. And the patients who have elevated GM-CSF early go on to be the patients who become severe and die. If they do start treating earlier stages, it might be a smaller dose that is given on a weekly basis until GM-CSF levels are lowered. Lenzilumab has the potential to be the SOC for milds, moderates, and severes.

This article explains GM-CSF's role in Covid:
https://www.bbc.com/news/health-56352128