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Re: jondoeuk post# 28

Tuesday, 05/25/2021 8:11:37 PM

Tuesday, May 25, 2021 8:11:37 PM

Post# of 302
I hope they continue to build and start to screen leukopaks for genomic and cellular characteristics that correlate with favourable clinical outcomes*. Also, removes exhausted and senescent cells (both before and after production), use translational data to identify other characteristics that contribute to (durable) response, improve the ex vivo expansion, and more.

* https://cancerdiscovery.aacrjournals.org/content/early/2021/04/05/2159-8290.CD-20-1677 https://www.nature.com/articles/s41591-020-1061-7 https://www.nature.com/articles/s41591-018-0010-1
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