Tuesday, May 25, 2021 6:58:21 PM
''AUTO1 has been designed to have an optimized interaction between its chimeric antigen receptor and the CD19 target on cancer cells,'' said Dr Martin Pule (Founder and CSO). ''This means AUTO1 can efficiently deliver a kill and disengage rapidly like a normal T-cell, leading to less exhaustion and less T-cell differentiation. This unique property of AUTO1 potentially contributes to the enrichment and maintenance of this stem cell memory subset that appears to be critical to the long-term durability observed in pediatric ALL patients treated with AUTO1.''
The paper https://www.nature.com/articles/s43018-021-00207-7
Recent AUTL News
- Abstract for longer-term follow-up and additional data analysis of Pivotal Phase 2 FELIX study of obe-cel for adult r/r B-ALL selected for an oral presentation at ASCO • GlobeNewswire Inc. • 04/24/2024 02:00:00 PM
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- Form D - Notice of Exempt Offering of Securities • Edgar (US Regulatory) • 02/23/2024 10:28:32 PM
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- Autolus Therapeutics announces acceptance of Biologics License Application for obecabtagene autoleucel (obe-cel) as a potential treatment for relapsed/refractory Adult B-cell Acute Lymphoblastic Leukemia (ALL) • GlobeNewswire Inc. • 01/22/2024 12:00:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 01/10/2024 08:12:17 PM
- Autolus Therapeutics announces the appointment of Robert W. Azelby to its Board of Directors • GlobeNewswire Inc. • 01/10/2024 12:00:00 PM
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