Sorrento Therapeutics Inc (SRNE)

[dia76ca]

How clever is Dr.Ji? He acquired SmartPharm for $20 million. SmartPharm then received $34 million in DARPA funding to produce a Covid fighting plasmid DNA. SmartPharm said, "We have used our tool box to create a scalable and cost-effective solution for creating pop-up immunity in people against coronavirus that has the capability to be rapidly scaled to deliver millions of doses. Our solution starts with our novel DNA plasmid that can express protein in muscle for weeks. This plasmid will be used to express an antibody capable of binding to and neutralizing the SARS-CoV-2 virus. This type of DNA plasmid has already been produced for other products in a fully cGMP-compliant manner and at significant quantities."

But this is only the beginning. Sorrento explained the wider implications saying..."The platform in synergy with Sorrento’s industry-leading fully human G-MAB™ antibody library has the potential to be the engine for the next-generation, cost-effective in vivo production of antibody therapeutics in patients. By encoding the antibody sequence into a plasmid, a single injection into someone’s muscle could potentially lead the person to make their own antibodies in vivo for months, instead of relying on repeat administrations of an externally manufactured antibody.

“We are very encouraged by the preclinical data generated thus far by our STI-2020dna plasmid candidate against COVID-19,” said Henry Ji, Ph.D., CEO of Sorrento Therapeutics. “But beyond STI-2020dna the integration of the plasmid DNA technology with our existing antibody products has the potential to make antibody therapy much more accessible and affordable for patients, and is applicable to a multitude of indications ranging from cancer to infectious diseases.”

Simply put Sorrento can now look forward to combining hundreds of different Mabs with SmartPharm's technology to fight hundreds of different cancers! ONE INJECTION TO PROVIDE A STEADY MULTI-MONTH STREAM OF MAB ACTIVITY INSTEAD OF COSTLY TIME CONSUMING WEEKLY INFUSIONS! This would revolutionize cancer treatments!