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Re: loanranger post# 357876

Monday, 05/03/2021 10:20:00 PM

Monday, May 03, 2021 10:20:00 PM

Post# of 402904
"...make the Brilacidin a most potent drug against SARS-CoV-2 than the known antiviral drugs."

Quite a quote and in a prestigious journal, no less.

Thanks for posting\,

Farrell

"Bio-computational designed Brilacidin is a synthetic non-peptide defensin mimic drug that destabilises the viral membrane by its amphipathic & hydrophobic nature, and its immunomodulatory property influence the expression of IL-1ß, IL-6, TNF-a cytokines, and cAMP& PDE4/PDE3 pathways which are associated with bronchodilator and anti-inflammatory effects of COVID-19 disease. The smaller size, more effective antimicrobial activity, bioavailability, low enzymatic degradation and toxicity, natural and low-cost production make the Brilacidin a most potent drug against SARS-CoV-2 than the known antiviral drugs."
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